On 12th May 2022, the Academy of Medical Royal Colleges issued new guidance for the UK on the recognition and management of sepsis, with particular emphasis of the timing of antimicrobial therapy with view to minimising the impact on AMR. Our new clinical tools, listed below, include tools which reflect this guidance for clinical areas using NEWS2 or the national paediatric early warning score (PEWS). Please fill out this form if you would like advice on which tool to use, or if you’d like to discuss adding your organisation’s logo or other detail to a tool.

The UK Sepsis Trust was founded by, and still receives senior leadership and strategic direction from, frontline clinicians passionate about improving outcomes from sepsis. Over the years, we have demonstrated leadership in this country and others in effecting systems change.

With this leadership comes responsibility. We are acutely aware of the intrinsic interrelationship between sepsis and antimicrobial resistance (AMR), and the potential societal impact which might result from getting the balance wrong. We’re committed to driving responsible improvement, to responding to new evidence and new ways of working, and to working collaboratively with agencies to ensure we deliver the care our patients need whilst minimising adverse consequences.

There is a lot we still don’t know about sepsis and severe infection, most particularly the lack of robust data on its incidence and outcomes. Whichever way you cut the existing data, however, sepsis is a huge problem. We have prepared below some responses to frequently asked questions to help you understand our mission, our values and our strategy for effecting change responsibly.